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Characterization of [(3)H]CFT binding to the norepinephrine transporter suggests that binding of CFT and nisoxetine is not mutually exclusive

The norepinephrine transporter (NET) is an important target for a wide variety of antidepressants and psychostimulants. Despite its prominence as a drug target, there is only one radioligand in use for NET competitive binding assays, [(3)H]nisoxetine. However, traditional [(3)H]nisoxetine binding pr...

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Detalhes bibliográficos
Main Authors: Zhen, Juan, Ali, Solav, Dutta, Aloke K., Reith, Maarten E.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221803/
https://ncbi.nlm.nih.gov/pubmed/21933682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2011.08.044
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