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Molecular Evolution of the Transmembrane Domains of G Protein-Coupled Receptors
G protein-coupled receptors (GPCRs) are a superfamily of integral membrane proteins vital for signaling and are important targets for pharmaceutical intervention in humans. Previously, we identified a group of ten amino acid positions (called key positions), within the seven transmembrane domain (7T...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221663/ https://ncbi.nlm.nih.gov/pubmed/22132149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027813 |
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