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Hydrophobicity profiles in G protein-coupled receptor transmembrane helical domains

The lack of a crystallographically derived structure for all but three G (TP [guanosine triphosphate]-binding) protein-coupled receptor (GPCRs) proteins necessitates the use of computationally derived methods to determine their structures. Computational methodologies allow a mechanistic glimpse into...

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Bibliografiska uppgifter
Huvudupphovsman: Crasto, Chiquito J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187720/
https://ncbi.nlm.nih.gov/pubmed/21984869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JRLCR.S14437
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