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Hydrophobicity profiles in G protein-coupled receptor transmembrane helical domains
The lack of a crystallographically derived structure for all but three G (TP [guanosine triphosphate]-binding) protein-coupled receptor (GPCRs) proteins necessitates the use of computationally derived methods to determine their structures. Computational methodologies allow a mechanistic glimpse into...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187720/ https://ncbi.nlm.nih.gov/pubmed/21984869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JRLCR.S14437 |
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