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Molecular Evolution of the Transmembrane Domains of G Protein-Coupled Receptors

G protein-coupled receptors (GPCRs) are a superfamily of integral membrane proteins vital for signaling and are important targets for pharmaceutical intervention in humans. Previously, we identified a group of ten amino acid positions (called key positions), within the seven transmembrane domain (7T...

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Hlavní autoři: Fatakia, Sarosh N., Costanzi, Stefano, Chow, Carson C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221663/
https://ncbi.nlm.nih.gov/pubmed/22132149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027813
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