The Effects of Glyburide on Apoptosis and Endoplasmic Reticulum Stress in INS-1 Cells in a Glucolipotoxic Condition

BACKGROUND: β-cell death due to endoplasmic reticulum (ER) stress has been regarded as an important pathogenic component of type 2 diabetes. The possibility has been suggested that sulfonylurea, currently being used as one of the main oral hypoglycemic agents of type 2 diabetes, increases ER stress,...

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Autores principales: Kwon, Min Jeong, Chung, Hye Suk, Yoon, Chang Shin, Ko, Jung Hae, Jun, Hae Jung, Kim, Tae Kyun, Lee, Soon Hee, Ko, Kyung Soo, Rhee, Byoung Doo, Kim, Mi Kyung, Park, Jeong Hyun
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Diabetes Association 2011
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221023/
https://ncbi.nlm.nih.gov/pubmed/22111039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2011.35.5.480
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