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Melatonin protects INS-1 pancreatic β-cells from apoptosis and senescence induced by glucotoxicity and glucolipotoxicity

INTRODUCTION: Melatonin is a hormone known as having very strong anti-oxidant property. Senescence is a biological state characterized by the loss of cell replication and the changes consisting of a pro-inflammatory phenotype, leading to Senescence Associated Secretory Phenotype (SASP) which is now...

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Détails bibliographiques
Publié dans:Islets
Auteurs principaux: Lee, Yu Hee, Jung, Hye Sook, Kwon, Min Jeong, Jang, Jung Eun, Kim, Tae Nyun, Lee, Soon Hee, Kim, Mi-Kyung, Park, Jeong Hyun
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7527021/
https://ncbi.nlm.nih.gov/pubmed/32673151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19382014.2020.1783162
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