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Small-molecule control of protein degradation using split adaptors

Targeted intracellular degradation provides a method to study the biological function of proteins and has numerous applications in biotechnology. One promising approach uses adaptor proteins to target substrates with genetically encoded degradation tags for proteolysis. Here, we describe an engineer...

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Bibliografski detalji
Glavni autori: Davis, Joseph H., Baker, Tania A., Sauer, Robert T.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220803/
https://ncbi.nlm.nih.gov/pubmed/21866931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2001389
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