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Small-molecule control of protein degradation using split adaptors

Targeted intracellular degradation provides a method to study the biological function of proteins and has numerous applications in biotechnology. One promising approach uses adaptor proteins to target substrates with genetically encoded degradation tags for proteolysis. Here, we describe an engineer...

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書誌詳細
主要な著者: Davis, Joseph H., Baker, Tania A., Sauer, Robert T.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220803/
https://ncbi.nlm.nih.gov/pubmed/21866931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2001389
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