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Structural Dynamics, Intrinsic Disorder, and Allostery in Nuclear Receptors as Transcription Factors
Steroid hormone receptors (SHRs) and nuclear receptors (NRs) in general are flexible, allosterically regulated transcription factors. The classic model is inadequate to explain all their behavior. Keys to function are their regions of intrinsic disorder (ID). Data show the dynamic structure and allo...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220581/ https://ncbi.nlm.nih.gov/pubmed/21937423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R111.278929 |
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