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Structural Dynamics, Intrinsic Disorder, and Allostery in Nuclear Receptors as Transcription Factors
Steroid hormone receptors (SHRs) and nuclear receptors (NRs) in general are flexible, allosterically regulated transcription factors. The classic model is inadequate to explain all their behavior. Keys to function are their regions of intrinsic disorder (ID). Data show the dynamic structure and allo...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Biochemistry and Molecular Biology
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220581/ https://ncbi.nlm.nih.gov/pubmed/21937423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R111.278929 |
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