Regulation of RCAN1 Protein Activity by Dyrk1A Protein-mediated Phosphorylation

Two genes on chromosome 21, namely dual specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) and regulator of calcineurin 1 (RCAN1), have been implicated in some of the phenotypic characteristics of Down syndrome, including the early onset of Alzheimer disease. Although a link between D...

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Autors principals: Jung, Min-Su, Park, Jung-Hwa, Ryu, Young Shin, Choi, Sun-Hee, Yoon, Song-Hee, Kwen, Mi-Yang, Oh, Ji Youn, Song, Woo-Joo, Chung, Sul-Hee
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220559/
https://ncbi.nlm.nih.gov/pubmed/21965663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253971
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