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NFATc1 phosphorylation by DYRK1A increases its protein stability

NFATs are transcription factors involved in immune activation and tumor progression. Previous reports showed that DYRK1A suppressed NFATc2 transcriptional activity through phosphorylation. Nonetheless, our results showed that DYRK1A increased NFATc1/αA protein level and subsequent transcriptional ac...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Heng, Wang, Ketao, Chen, Shuai, Sun, Qian, Zhang, Yuankai, Chen, Long, Sun, Xiulian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325557/
https://ncbi.nlm.nih.gov/pubmed/28235034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172985
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