Wird geladen...

NFATc1 phosphorylation by DYRK1A increases its protein stability

NFATs are transcription factors involved in immune activation and tumor progression. Previous reports showed that DYRK1A suppressed NFATc2 transcriptional activity through phosphorylation. Nonetheless, our results showed that DYRK1A increased NFATc1/αA protein level and subsequent transcriptional ac...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Liu, Heng, Wang, Ketao, Chen, Shuai, Sun, Qian, Zhang, Yuankai, Chen, Long, Sun, Xiulian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325557/
https://ncbi.nlm.nih.gov/pubmed/28235034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172985
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!