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A Conserved Acidic Motif Is Crucial for Enzymatic Activity of Protein O-Mannosyltransferases
Protein O-mannosylation is an essential modification in fungi and mammals. It is initiated at the endoplasmic reticulum by a conserved family of dolichyl phosphate mannose-dependent protein O-mannosyltransferases (PMTs). PMTs are integral membrane proteins with two hydrophilic loops (loops 1 and 5)...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220539/ https://ncbi.nlm.nih.gov/pubmed/21956107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.281196 |
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