Conformational Plasticity of the Essential Membrane-associated Mannosyltransferase PimA from Mycobacteria

Phosphatidyl-myo-inositol mannosyltransferase A (PimA) is an essential glycosyltransferase (GT) that initiates the biosynthetic pathway of phosphatidyl-myo-inositol mannosides, lipomannan, and lipoarabinomannan, which are key glycolipids/lipoglycans of the mycobacterial cell envelope. PimA belongs t...

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Detalles Bibliográficos
Main Authors: Giganti, David, Alegre-Cebollada, Jorge, Urresti, Saioa, Albesa-Jové, David, Rodrigo-Unzueta, Ane, Comino, Natalia, Kachala, Michael, López-Fernández, Sonia, Svergun, Dmitri I., Fernández, Julio M., Guerin, Marcelo E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Glycobiology and Extracellular Matrices
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795279/
https://ncbi.nlm.nih.gov/pubmed/23963451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.462705
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