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Controlled Expression of Branch-forming Mannosyltransferase Is Critical for Mycobacterial Lipoarabinomannan Biosynthesis
Lipomannan (LM) and lipoarabinomannan (LAM) are phosphatidylinositol-anchored glycans present in the mycobacterial cell wall. In Mycobacterium smegmatis, the mannan core of LM/LAM constitutes a linear chain of 20–25 α1,6-mannoses elaborated by 8–9 α1,2-monomannose side branches. At least two α1,6-ma...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2859491/ https://ncbi.nlm.nih.gov/pubmed/20215111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077297 |
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