Controlled Expression of Branch-forming Mannosyltransferase Is Critical for Mycobacterial Lipoarabinomannan Biosynthesis

Lipomannan (LM) and lipoarabinomannan (LAM) are phosphatidylinositol-anchored glycans present in the mycobacterial cell wall. In Mycobacterium smegmatis, the mannan core of LM/LAM constitutes a linear chain of 20–25 α1,6-mannoses elaborated by 8–9 α1,2-monomannose side branches. At least two α1,6-ma...

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Detalhes bibliográficos
Main Authors: Sena, Chubert B. C., Fukuda, Takeshi, Miyanagi, Kana, Matsumoto, Sohkichi, Kobayashi, Kazuo, Murakami, Yoshiko, Maeda, Yusuke, Kinoshita, Taroh, Morita, Yasu S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859491/
https://ncbi.nlm.nih.gov/pubmed/20215111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.077297
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