TNF-α and IL-1β Promote a Disintegrin-like and Metalloprotease with Thrombospondin Type I Motif-5-mediated Aggrecan Degradation through Syndecan-4 in Intervertebral Disc

Elevated levels of TNF-α, IL-1β and a resultant increase in ADAMTS (a disintegrin-like and metalloprotease with thrombospondin type I motifs) expression is seen during disc degeneration. However, if these pro-inflammatory cytokines control ADAMTS activity is not definitively known. The goal of the i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wang, Jianru, Markova, Dessislava, Anderson, D. Greg, Zheng, Zhaomin, Shapiro, Irving M., Risbud, Makarand V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Glycobiology and Extracellular Matrices
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220535/
https://ncbi.nlm.nih.gov/pubmed/21949132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.264549
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak