p21-activated Kinase 3 (PAK3) Protein Regulates Synaptic Transmission through Its Interaction with the Nck2/Grb4 Protein Adaptor

Mutations in the p21-activated kinase 3 gene (pak3) are responsible for nonsyndromic forms of mental retardation. Expression of mutated PAK3 proteins in hippocampal neurons induces abnormal dendritic spine morphology and long term potentiation anomalies, whereas pak3 gene invalidation leads to cogni...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thévenot, Emmanuel, Moreau, Alexandre William, Rousseau, Véronique, Combeau, Gaëlle, Domenichini, Florence, Jacquet, Claire, Goupille, Olivier, Amar, Muriel, Kreis, Patricia, Fossier, Philippe, Barnier, Jean-Vianney
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220523/
https://ncbi.nlm.nih.gov/pubmed/21949127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.262246
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