Alteration of Synaptic Network Dynamics by the Intellectual Disability Protein PAK3

Several gene mutations linked to intellectual disability in humans code for synaptic molecules implicated in small GTPase signaling. This is the case of the Rac/Cdc42 effector p21-activated kinase 3 (PAK3). The mechanisms responsible for the intellectual defects and the consequences of the mutation...

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Pubblicato in:J Neurosci
Autori principali: Dubos, Aline, Combeau, Gaelle, Bernardinelli, Yann, Barnier, Jean-Vianney, Hartley, Oliver, Gaertner, Hubert, Boda, Bernadett, Muller, Dominique
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621069/
https://ncbi.nlm.nih.gov/pubmed/22238087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3252-11.2012
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