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Crystal Structure of Fcγ Receptor I and Its Implication in High Affinity γ-Immunoglobulin Binding

Fcγ receptors (FcγRs) play critical roles in humoral and cellular immune responses through interactions with the Fc region of immunoglobulin G (IgG). Among them, FcγRI is the only high affinity receptor for IgG and thus is a potential target for immunotherapy. Here we report the first crystal struct...

詳細記述

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書誌詳細
主要な著者: Lu, Jinghua, Ellsworth, Jeff L., Hamacher, Nels, Oak, Si Won, Sun, Peter D.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220521/
https://ncbi.nlm.nih.gov/pubmed/21965667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.257550
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