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Crystal Structure of Fcγ Receptor I and Its Implication in High Affinity γ-Immunoglobulin Binding
Fcγ receptors (FcγRs) play critical roles in humoral and cellular immune responses through interactions with the Fc region of immunoglobulin G (IgG). Among them, FcγRI is the only high affinity receptor for IgG and thus is a potential target for immunotherapy. Here we report the first crystal struct...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220521/ https://ncbi.nlm.nih.gov/pubmed/21965667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.257550 |
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