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Ultra-Efficient PrP(Sc) Amplification Highlights Potentialities and Pitfalls of PMCA Technology
In order to investigate the potential of voles to reproduce in vitro the efficiency of prion replication previously observed in vivo, we seeded protein misfolding cyclic amplification (PMCA) reactions with either rodent-adapted Transmissible Spongiform Encephalopathy (TSE) strains or natural TSE iso...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219717/ https://ncbi.nlm.nih.gov/pubmed/22114554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002370 |
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