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In vitro replication highlights the mutability of prions
Prions exist as strains, which are thought to reflect PrP(Sc) conformational variants. Prion strains can mutate and it has been proposed that prion mutability depends on an intrinsic heterogeneity of prion populations that would behave as quasispecies. We investigated in vitro prion mutability of 2...
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| Publicado no: | Prion |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7030905/ https://ncbi.nlm.nih.gov/pubmed/24618479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.28468 |
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