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Molecular Pathogenesis of Secondary Acute Promyelocytic Leukemia
Balanced chromosomal translocations that generate chimeric oncoproteins are considered to be initiating lesions in the pathogenesis of acute myeloid leukemia. The most frequent is the t(15;17)(q22;q21), which fuses the PML and RARA genes, giving rise to acute promyelocytic leukemia (APL). An increas...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Università Cattolica del Sacro Cuore
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219647/ https://ncbi.nlm.nih.gov/pubmed/22110895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4084/MJHID.2011.045 |
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