Active Bax and Bak are functional holins

The mechanism of Bax/Bak-dependent mitochondrial outer membrane permeabilization (MOMP), a central apoptotic event primarily controlled by the Bcl-2 family proteins, remains not well understood. Here, we express active Bax/Bak in bacteria, the putative origin of mitochondria, and examine their funct...

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Main Authors: Pang, Xiaming, Moussa, Samir H., Targy, Natalie M., Bose, Jeffrey L., George, Nicholas M., Gries, Casey, Lopez, Hernando, Zhang, Liqiang, Bayles, Kenneth W., Young, Ry, Luo, Xu
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2011
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219232/
https://ncbi.nlm.nih.gov/pubmed/22006182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.171645.111
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