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Breast cancer cell migration is regulated through junctional adhesion molecule-A-mediated activation of Rap1 GTPase
INTRODUCTION: The adhesion protein junctional adhesion molecule-A (JAM-A) regulates epithelial cell morphology and migration, and its over-expression has recently been linked with increased risk of metastasis in breast cancer patients. As cell migration is an early requirement for tumor metastasis,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219194/ https://ncbi.nlm.nih.gov/pubmed/21429211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2853 |
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