A novel mechanism of regulating breast cancer cell migration via palmitoylation-dependent alterations in the lipid raft affiliation of CD44

INTRODUCTION: Most breast cancer-related deaths result from metastasis, a process involving dynamic regulation of tumour cell adhesion and migration. The adhesion protein CD44, a key regulator of cell migration, is enriched in cholesterol-enriched membrane microdomains termed lipid rafts. We recentl...

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Detalhes bibliográficos
Main Authors: Babina, Irina S, McSherry, Elaine A, Donatello, Simona, Hill, Arnold DK, Hopkins, Ann M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978828/
https://ncbi.nlm.nih.gov/pubmed/24512624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3614
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