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Lipid Raft Association Restricts CD44-Ezrin Interaction and Promotion of Breast Cancer Cell Migration
Cancer cell migration is an early event in metastasis, the main cause of breast cancer-related deaths. Cholesterol-enriched membrane domains called lipid rafts influence the function of many molecules, including the raft-associated protein CD44. We describe a novel mechanism whereby rafts regulate i...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
American Society for Investigative Pathology
2012
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3502863/ https://ncbi.nlm.nih.gov/pubmed/23031255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.08.025 |
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