Lipid Raft Association Restricts CD44-Ezrin Interaction and Promotion of Breast Cancer Cell Migration

Cancer cell migration is an early event in metastasis, the main cause of breast cancer-related deaths. Cholesterol-enriched membrane domains called lipid rafts influence the function of many molecules, including the raft-associated protein CD44. We describe a novel mechanism whereby rafts regulate i...

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Autors principals: Donatello, Simona, Babina, Irina S., Hazelwood, Lee D., Hill, Arnold D.K., Nabi, Ivan R., Hopkins, Ann M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2012
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3502863/
https://ncbi.nlm.nih.gov/pubmed/23031255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.08.025
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