Malaria antifolate resistance with contrasting Plasmodium falciparum dihydrofolate reductase (DHFR) polymorphisms in humans and Anopheles mosquitoes

Surveillance for drug-resistant parasites in human blood is a major effort in malaria control. Here we report contrasting antifolate resistance polymorphisms in Plasmodium falciparum when parasites in human blood were compared with parasites in Anopheles vector mosquitoes from sleeping huts in rural...

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Bibliographic Details
Main Authors: Mharakurwa, Sungano, Kumwenda, Taida, Mkulama, Mtawa A. P., Musapa, Mulenga, Chishimba, Sandra, Shiff, Clive J., Sullivan, David J., Thuma, Philip E., Liu, Kun, Agre, Peter
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219121/
https://ncbi.nlm.nih.gov/pubmed/22065788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116162108
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