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Sunitinib inhibits lymphatic endothelial cell functions and lymph node metastasis in a breast cancer model through inhibition of vascular endothelial growth factor receptor 3

INTRODUCTION: Metastasis is a common event and the main cause of death in cancer patients. Lymphangiogenesis refers to the formation of new lymphatic vessels and is thought to be involved in the development of metastasis. Sunitinib is a multi-kinase inhibitor that blocks receptor tyrosine kinase act...

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Sonraí Bibleagrafaíochta
Main Authors: Kodera, Yasuo, Katanasaka, Yasufumi, Kitamura, Yuka, Tsuda, Hitoshi, Nishio, Kazuto, Tamura, Tomohide, Koizumi, Fumiaki
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218955/
https://ncbi.nlm.nih.gov/pubmed/21693010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2903
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