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Apoptotic Peptides Derived from HIV-1 Nef Induce Lymphocyte Depletion in Mice

INTRODUCTION: We have developed a mouse model to examine the effects of host exposure (ie, hematopoietic system) to secreted HIV-1 Nef or peptides derived from Nef. METHODS: We used a combination of terminal uridine deoxynucleotidyl transferase (dUTP) nick end labeling (TUNEL) assays and CD4+ cell c...

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Main Authors: Huang, Ming-Bo, James, Cleve O., Powell, Michael D., Bond, Vincent C.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218084/
https://ncbi.nlm.nih.gov/pubmed/18646317
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