Chemogenomic profiling: Identifying the functional interactions of small molecules in yeast

We demonstrate the efficacy of a genome-wide protocol in yeast that allows the identification of those gene products that functionally interact with small molecules and result in the inhibition of cellular proliferation. Here we present results from screening 10 diverse compounds in 80 genome-wide e...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Giaever, Guri, Flaherty, Patrick, Kumm, Jochen, Proctor, Michael, Nislow, Corey, Jaramillo, Daniel F., Chu, Angela M., Jordan, Michael I., Arkin, Adam P., Davis, Ronald W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718668/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307490100
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