Chemogenomic profiling: Identifying the functional interactions of small molecules in yeast

We demonstrate the efficacy of a genome-wide protocol in yeast that allows the identification of those gene products that functionally interact with small molecules and result in the inhibition of cellular proliferation. Here we present results from screening 10 diverse compounds in 80 genome-wide e...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Giaever, Guri, Flaherty, Patrick, Kumm, Jochen, Proctor, Michael, Nislow, Corey, Jaramillo, Daniel F., Chu, Angela M., Jordan, Michael I., Arkin, Adam P., Davis, Ronald W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321760/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14718668/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307490100
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