Genome-Wide Requirements for Resistance to Functionally Distinct DNA-Damaging Agents

The mechanistic and therapeutic differences in the cellular response to DNA-damaging compounds are not completely understood, despite intense study. To expand our knowledge of DNA damage, we assayed the effects of 12 closely related DNA-damaging agents on the complete pool of ~4,700 barcoded homozyg...

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Main Authors: Lee, William, St.Onge, Robert P, Proctor, Michael, Flaherty, Patrick, Jordan, Michael I, Arkin, Adam P, Davis, Ronald W, Nislow, Corey, Giaever, Guri
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2005
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189734/
https://ncbi.nlm.nih.gov/pubmed/16121259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0010024
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