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Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions

Systematic genetic interaction studies have illuminated many cellular processes. Here we quantitatively examine genetic interactions among 26 Saccharomyces cerevisiae genes conferring resistance to the DNA-damaging agent methyl methanesulfonate (MMS), as determined by chemogenomic fitness profiling...

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Main Authors: St Onge, Robert P, Mani, Ramamurthy, Oh, Julia, Proctor, Michael, Fung, Eula, Davis, Ronald W, Nislow, Corey, Roth, Frederick P, Giaever, Guri
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716756/
https://ncbi.nlm.nih.gov/pubmed/17206143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1948
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