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Systematic pathway analysis using high-resolution fitness profiling of combinatorial gene deletions
Systematic genetic interaction studies have illuminated many cellular processes. Here we quantitatively examine genetic interactions among 26 Saccharomyces cerevisiae genes conferring resistance to the DNA-damaging agent methyl methanesulfonate (MMS), as determined by chemogenomic fitness profiling...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716756/ https://ncbi.nlm.nih.gov/pubmed/17206143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1948 |
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