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Defining genetic interaction

Sometimes mutations in two genes produce a phenotype that is surprising in light of each mutation's individual effects. This phenomenon, which defines genetic interaction, can reveal functional relationships between genes and pathways. For example, double mutants with surprisingly slow growth d...

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Detalhes bibliográficos
Main Authors: Mani, Ramamurthy, St.Onge, Robert P., Hartman, John L., Giaever, Guri, Roth, Frederick P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265146/
https://ncbi.nlm.nih.gov/pubmed/18305163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712255105
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