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The Synthetic Genetic Interaction Network Reveals Small Molecules that Target Specific Pathways in Sacchromyces cerevisiae

High-throughput elucidation of synthetic genetic interactions (SGIs) has contributed to a systems-level understanding of genetic robustness and fault-tolerance encoded in the genome. Pathway targets of various compounds have been predicted by comparing chemical-genetic synthetic interactions to a ne...

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Detalhes bibliográficos
Publicado no:Mol Biosyst
Main Authors: Tamble, Craig M., St Onge, Robert P., Giaever, Guri, Nislow, Corey, Williams, Alexander G., Stuart, Joshua M., Lokey, R. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4653045/
https://ncbi.nlm.nih.gov/pubmed/21487606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mb00298d
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