Accelerating the Discovery of Biologically Active Small Molecules Using a High-Throughput Yeast Halo Assay

The budding yeast Saccharomyces cerevisiae, a powerful model system for the study of basic eukaryotic cell biology, has been used increasingly as a screening tool for the identification of bioactive small molecules. We have developed a novel yeast toxicity screen that is easily automated and compati...

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Hauptverfasser: Gassner, Nadine C., Tamble, Craig M., Bock, Jonathan E., Cotton, Naomi, White, Kimberly N., Tenney, Karen, St. Onge, Robert P., Proctor, Michael J., Giaever, Guri, Davis, Ronald W., Crews, Phillip, Holman, Theodore R., Lokey, R. Scott
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533267/
https://ncbi.nlm.nih.gov/pubmed/17291044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np060555t
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