Accelerating the Discovery of Biologically Active Small Molecules Using a High-Throughput Yeast Halo Assay

The budding yeast Saccharomyces cerevisiae, a powerful model system for the study of basic eukaryotic cell biology, has been used increasingly as a screening tool for the identification of bioactive small molecules. We have developed a novel yeast toxicity screen that is easily automated and compati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gassner, Nadine C., Tamble, Craig M., Bock, Jonathan E., Cotton, Naomi, White, Kimberly N., Tenney, Karen, St. Onge, Robert P., Proctor, Michael J., Giaever, Guri, Davis, Ronald W., Crews, Phillip, Holman, Theodore R., Lokey, R. Scott
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2007
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533267/
https://ncbi.nlm.nih.gov/pubmed/17291044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np060555t
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