Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action

We systematically analyzed the relationships between gene fitness profiles (co-fitness) and drug inhibition profiles (co-inhibition) from several hundred chemogenomic screens in yeast. Co-fitness predicted gene functions distinct from those derived from other assays and identified conditionally depe...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Hillenmeyer, Maureen E, Ericson, Elke, Davis, Ronald W, Nislow, Corey, Koller, Daphne, Giaever, Guri
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864570/
https://ncbi.nlm.nih.gov/pubmed/20226027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-3-r30
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker