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Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast

To better understand off-target effects of widely prescribed psychoactive drugs, we performed a comprehensive series of chemogenomic screens using the budding yeast Saccharomyces cerevisiae as a model system. Because the known human targets of these drugs do not exist in yeast, we could employ the y...

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Detaylı Bibliyografya
Asıl Yazarlar: Ericson, Elke, Gebbia, Marinella, Heisler, Lawrence E., Wildenhain, Jan, Tyers, Mike, Giaever, Guri, Nislow, Corey
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483942/
https://ncbi.nlm.nih.gov/pubmed/18688276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000151
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