A survey of yeast genomic assays for drug and target discovery

Over the past decade, the development and application of chemical genomic assays using the model organism Saccharomyces cerevisiae has provided powerful methods to identify the mechanism of action of known drugs and novel small molecules in vivo. These assays identify drug target candidates, genes i...

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Main Authors: Smith, Andrew M., Ammar, Ron, Nislow, Corey, Giaever, Guri
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923554/
https://ncbi.nlm.nih.gov/pubmed/20546776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2010.04.012
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