Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action

We systematically analyzed the relationships between gene fitness profiles (co-fitness) and drug inhibition profiles (co-inhibition) from several hundred chemogenomic screens in yeast. Co-fitness predicted gene functions distinct from those derived from other assays and identified conditionally depe...

Full description

Saved in:
Bibliographic Details
Main Authors: Hillenmeyer, Maureen E, Ericson, Elke, Davis, Ronald W, Nislow, Corey, Koller, Daphne, Giaever, Guri
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Method
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864570/
https://ncbi.nlm.nih.gov/pubmed/20226027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-3-r30
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items