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An intact PDZ motif is essential for correct P2Y(12) purinoceptor traffic in human platelets
The platelet P2Y(12) purinoceptor (P2Y(12)R), which plays a crucial role in hemostasis, undergoes internalization and subsequent recycling to maintain receptor responsiveness, processes that are essential for normal platelet function. Here, we observe that P2Y(12)R function is compromised after dele...
में बचाया:
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society of Hematology
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3217363/ https://ncbi.nlm.nih.gov/pubmed/21937696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-336826 |
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