An intact PDZ motif is essential for correct P2Y(12) purinoceptor traffic in human platelets

The platelet P2Y(12) purinoceptor (P2Y(12)R), which plays a crucial role in hemostasis, undergoes internalization and subsequent recycling to maintain receptor responsiveness, processes that are essential for normal platelet function. Here, we observe that P2Y(12)R function is compromised after dele...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nisar, Shaista, Daly, Martina E., Federici, Augusto B., Artoni, Andrea, Mumford, Andrew D., Watson, Stephen P., Mundell, Stuart J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2011
Pynciau:
Platelets and Thrombopoiesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217363/
https://ncbi.nlm.nih.gov/pubmed/21937696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-336826
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg