Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity

BACKGROUND: The 90-kDa ribosomal S6 kinase (Rsk) family is involved in cell survival. Rsk activation is regulated by sequential phosphorylations controlled by extracellular signal-regulated kinase (ERK) 1/2 and 3-phosphoinositide-dependent protein kinase 1 (PDK1). Altered ERK1/2 and PDK1 phosphoryla...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Xifró, Xavier, Anglada-Huguet, Marta, Rué, Laura, Saavedra, Ana, Pérez-Navarro, Esther, Alberch, Jordi
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217046/
https://ncbi.nlm.nih.gov/pubmed/22041125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-74
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk