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Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum
The human malaria parasite Plasmodium falciparum is responsible for the deaths of more than a million people each year. Fosmidomycin has been proven to be efficient in the treatment of P. falciparum malaria by inhibiting 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR), an enzyme of the non-mev...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3216497/ https://ncbi.nlm.nih.gov/pubmed/22355528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00009 |
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