Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species

Unraveling the gene regulatory networks that govern development and function of the mammalian heart is critical for the rational design of therapeutic interventions in human heart disease. Using the Drosophila heart as a platform for identifying novel gene interactions leading to heart disease, we f...

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Bibliografiske detaljer
Main Authors: Qian, Li, Wythe, Joshua D., Liu, Jiandong, Cartry, Jerome, Vogler, Georg, Mohapatra, Bhagyalaxmi, Otway, Robyn T., Huang, Yu, King, Isabelle N., Maillet, Marjorie, Zheng, Yi, Crawley, Timothy, Taghli-Lamallem, Ouarda, Semsarian, Christopher, Dunwoodie, Sally, Winlaw, David, Harvey, Richard P., Fatkin, Diane, Towbin, Jeffrey A., Molkentin, Jeffery D., Srivastava, Deepak, Ocorr, Karen, Bruneau, Benoit G., Bodmer, Rolf
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216339/
https://ncbi.nlm.nih.gov/pubmed/21690310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201006114
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