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Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease
neuromancer/Tbx20 (nmr) genes are cardiac T-box transcription factors that are evolutionarily conserved from flies to humans. Along with other known congenital heart disease genes, including tinman/Nkx2–5, dorsocross/Tbx5/6, and pannier/Gata4/6, they are important for specification and morphogenesis...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605007/ https://ncbi.nlm.nih.gov/pubmed/19074289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808705105 |
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