Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease

neuromancer/Tbx20 (nmr) genes are cardiac T-box transcription factors that are evolutionarily conserved from flies to humans. Along with other known congenital heart disease genes, including tinman/Nkx2–5, dorsocross/Tbx5/6, and pannier/Gata4/6, they are important for specification and morphogenesis...

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Bibliographic Details
Main Authors: Qian, Li, Mohapatra, Bhagyalaxmi, Akasaka, Takeshi, Liu, Jiandong, Ocorr, Karen, Towbin, Jeffrey A., Bodmer, Rolf
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605007/
https://ncbi.nlm.nih.gov/pubmed/19074289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808705105
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