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Mechanical and non-mechanical functions of Dystrophin can prevent cardiac abnormalities in Drosophila

Dystrophin-deficiency causes cardiomyopathies and shortens the life expectancy of Duchenne and Becker muscular dystrophy patients. Restoring Dystrophin expression in the heart by gene transfer is a promising avenue to explore as a therapy. Truncated Dystrophin gene constructs have been engineered an...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Taghli-Lamallem, Ouarda, Jagla, Krzysztof, Chamberlain, Jeffrey S., Bodmer, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340692/
https://ncbi.nlm.nih.gov/pubmed/24231130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2013.10.015
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