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Lipotoxicity and cardiac dysfunction in mammals and Drosophila

The lipotoxic effects of obesity are important contributing factors in cancer, diabetes, and cardiovascular disease (CVD), but the genetic mechanisms, by which lipotoxicity influences the initiation and progression of CVD are poorly understood. Hearts, of obese and diabetic individuals, exhibit seve...

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Bibliographic Details
Published in:Crit Rev Biochem Mol Biol
Main Authors: Birse, Ryan Tyge, Bodmer, Rolf
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386717/
https://ncbi.nlm.nih.gov/pubmed/21851295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2011.599830
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